ADRA1B
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| ADRA1B | Frequent reduced expression of alpha-1B-adrenergic receptor caused by aberrant promoter methylation in gastric cancers | 17242706 | ADRA1B gene is an important tumour-related gene frequently involved in the development and progression of gastric cancer | mechanism | BC/OC research |
| ADRA1B | beta-Adrenoreceptor antagonists reduce cancer cell proliferation, invasion, and migration | 25026350 | The ADRA1B expression was found to be higher in MCF7 cells, which is expressed 2-fold higher than HT-29 cells and 10-fold higher than HepG2 cells | mechanism | BC/OC research |
| ADRA1B | The prognostic value of ADRA1 subfamily genes in gastric carcinoma | 31452791 | Multivariate survival analysis revealed that low expression levels of ADRA1A (HR, 0.595; 95% CI, 0.426 0.831; adjusted P=0.002) ADRA1B (HR, 0.576; 95% CI, 0.412 0.805; adjusted P=0.001) and ADRA1D (HR, 0.559; 95% CI, 0.398 0.787; adjusted P=0.001) were associated with a favourable OS | biomarker | BC/OC research |
Survival analysis
Pathway
| Pathway Term | Reference DB | |
|---|---|---|
| ADRA1B | hsa04970:Salivary secretion | KEGG |
| ADRA1B | Monoamine GPCRs (Homo sapiens) | Wikipathway |
| ADRA1B | Calcium Regulation in the Cardiac Cell (Homo sapiens) | Wikipathway |
| ADRA1B | GPCRs, Class A Rhodopsin-like (Homo sapiens) | Wikipathway |
| ADRA1B | Vitamin D Receptor Pathway (Homo sapiens) | Wikipathway |
| ADRA1B | Gastrin-CREB signalling pathway via PKC and MAPK (Homo sapiens) | Wikipathway |
| ADRA1B | GPCR ligand binding (Homo sapiens) | Wikipathway |
| ADRA1B | GPCR downstream signaling (Homo sapiens) | Wikipathway |
| ADRA1B | AMP-activated Protein Kinase (AMPK) Signaling (Homo sapiens) | Wikipathway |
| ADRA1B | hsa04270:Vascular smooth muscle contraction | KEGG |