hsa-miR-200
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| hsa-miR-200 | miR-200 enhances mouse breast cancer cell colonization to form distant metastases | 19787069 | Expression of miR-200, which promotes a mesenchymal to epithelial cell transition (MET) by inhibiting Zeb2 expression, unexpectedly enhances macroscopic metastases in mouse breast cancer cell lines | mechanism | BC/OC research |
| hsa-miR-200 | Epigenetic modulation of the miR-200 family is associated with transition to a breast cancer stem-cell-like state | 23525011 | These results indicate that the miR-200 family plays a crucial role in the transition between stem-like and non-stem phenotypes and that distinct epigenetic-based mechanisms regulate each miR-200 gene in this process | mechanism | BC/OC research |
| hsa-miR-200 | MiR-200 can repress breast cancer metastasis through ZEB1-independent but moesin-dependent pathways | 24037528 | These findings highlight the context-dependent effects of miR-200 in breast cancer metastasis and demonstrate the existence of a moesin-dependent pathway, distinct from the ZEB1-E-cadherin axis, through which miR-200 can regulate tumour cell plasticity and metastasis | mechanism | BC/OC research |
| hsa-miR-200 | miR-200-containing extracellular vesicles promote breast cancer cell metastasis | 25401471 | In murine cancer and human xenograft models, miR-200-expressing tumors and extracellular vesicles from these tumors promoted metastasis of otherwise weakly metastatic cells either nearby or at distant sites and conferred to these cells the ability to colonize distant tissues in a miR-200-dependent manner | mechanism | BC/OC research |
| hsa-miR-200 | MicroRNA-200, associated with metastatic breast cancer, promotes traits of mammary luminal progenitor cells | 29137351 | We propose that microRNAs of the miR-200 family promote traits of highly proliferative breast luminal progenitor cells, thereby exacerbating the growth and metastatic properties of transformed mammary epithelial cells | mechanism | BC/OC research |
| hsa-miR-200 | hsa-miR-200-containing extracellular vesicles promote breast cancer cell metastasis | 28038441 | Promote mesenchymal-to-epithelial transition and colonisation of metastatic sites | mechanism | BCEXO research |
Survival analysis