GSTP1
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| GSTP1 | Cruciferous vegetables, the GSTP1 Ile105Val genetic polymorphism, and breast cancer risk | 18326615 | Cruciferous vegetable intake consistent with high isothiocyanate exposure may reduce breast cancer risk. Cruciferous vegetable intake also may ameliorate the effects of the GSTP1 genotype | mechanism | BC/OC research |
| GSTP1 | GSTP1 methylation and polymorphism increase the risk of breast cancer and the effects of diet and lifestyle in breast cancer patients | 23226781 | GSTP1 methylation is a major event in breast carcinogenesis and may act as a tumor-specific biomarker | biomarker | BC/OC research |
| GSTP1 | The GSTP1 105Val Allele Increases Breast Cancer Risk and Aggressiveness but Enhances Response to Cyclophosphamide Chemotherapy in North China | 23826324 | GSTP1 Ile105Val genotype may help screen for high-risk populations and direct individualized therapy | mechanism | BC/OC research |
| GSTP1 | Association of GSTP1 Methylation with Aggressive Phenotype in ER-positive Breast Cancer | 24324107 | GSTP1 methylation may well be associated with the pathogenesis of the biologically-aggressive phenotype in ER-positive breast cancer | mechanism | BC/OC research |
| GSTP1 | GSTP1 Is a Driver of Triple-Negative Breast Cancer Cell Metabolism and Pathogenicity | 27185638 | GSTP1 inhibitors as a novel?therapeutic strategy for combatting TNBCs through impairing key cancer metabolism and signaling pathways | mechanism | BC/OC research |
| GSTP1 | Prognostic significance of GSTP1 in patients with triple negative breast cancer | 28978147 | GSTP1 protein may be a novel prognosis marker for TNBC patients in China | biomarker | BC/OC research |
| GSTP1 | CLDN6 promotes chemoresistance through GSTP1 in human breast cancer | 29116019 | High expression of CLDN6 confers chemoresistance on breast cancer which is mediated by GSTP1, the activity of which is regulated by p53 | mechanism | BC/OC research |
| GSTP1 | Predictive role of GSTP1-containing exosomes in chemotherapy-resistant breast cancer | 28438694 | Affecting drug metabolism---Anthracycline/taxane-based neoadjuvant chemotherapy | mechanism | BCEXO research |
Survival analysis
Pathway
| Pathway Term | Reference DB | |
|---|---|---|
| GSTP1 | Phase II - Conjugation of compounds (Homo sapiens) | Wikipathway |
| GSTP1 | Metapathway biotransformation Phase I and II (Homo sapiens) | Wikipathway |
| GSTP1 | R-HSA-156590 | Reactome |
| GSTP1 | R-HSA-3299685 | Reactome |
| GSTP1 | hsa00480:Glutathione metabolism | KEGG |
| GSTP1 | hsa00980:Metabolism of xenobiotics by cytochrome P450 | KEGG |
| GSTP1 | hsa00982:Drug metabolism - cytochrome P450 | KEGG |
| GSTP1 | hsa05204:Chemical carcinogenesis | KEGG |
| GSTP1 | Detoxification of Reactive Oxygen Species (Homo sapiens) | Wikipathway |
| GSTP1 | Nuclear Receptors Meta-Pathway (Homo sapiens) | Wikipathway |