ABCB11
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| ABCB11 | Description of two new ABCB11 mutations responsible for type 2 benign recurrent intrahepatic cholestasis in a French-Canadian family | 21766090 | The present report describes two individuals from the same family whose symptoms were typical of the clinical characteristics of type 2 benign recurrent intrahepatic cholestasis. Sequencing of the?ABCB11?gene revealed two previously unreported mutations that predict the absence of expression of the protein | mechanism | BC/OC research |
| ABCB11 | The role of ABC transporters in progression and clinical outcome of colorectal cancer | 22294766 | ABCC11 may be a promising candidate marker for a validation study on 5-FU therapy outcome | biomarker | BC/OC research |
| ABCB11 | Paediatric hepatocellular carcinoma due to somatic CTNNB1 and NFE2L2 mutations in the setting of inherited bi-allelic ABCB11 mutations | 25016225 | This is the first study to identify somatic CTNNB1 and NFE2L2 mutations in early childhood arisen in the setting of inherited bi-allelic ABCB11 mutations | mechanism | BC/OC research |
Survival analysis
Pathway
| Pathway Term | Reference DB | |
|---|---|---|
| ABCB11 | R-HSA-159418 | Reactome |
| ABCB11 | R-HSA-193368 | Reactome |
| ABCB11 | R-HSA-5678520 | Reactome |
| ABCB11 | hsa02010:ABC transporters | KEGG |
| ABCB11 | hsa04976:Bile secretion | KEGG |
| ABCB11 | Bile acid and bile salt metabolism (Homo sapiens) | Wikipathway |
| ABCB11 | Drug Induction of Bile Acid Pathway (Homo sapiens) | Wikipathway |
| ABCB11 | Farnesoid X Receptor Pathway (Homo sapiens) | Wikipathway |
| ABCB11 | Nuclear Receptors Meta-Pathway (Homo sapiens) | Wikipathway |
| ABCB11 | Nuclear Receptors in Lipid Metabolism and Toxicity (Homo sapiens) | Wikipathway |