MRPS30
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| MRPS30 | Novel breast cancer risk alleles and interaction with ionizing radiation among U.S. radiologic technologists | 20095854 | The radiation-associated breast cancer risk varied significantly by linked markers in 5p12 (rs930395, rs10941679, rs2067980 and rs4415084) in the mitochondrial ribosomal protein S30 (MRPS30) gene (P(interaction) = 0.04) | mechanism | BC/OC research |
| MRPS30 | Genetic variants in the?MRPS30?region and postmenopausal breast cancer risk | 21702935 | Combined main effect and intervention interaction analyses raise novel hypotheses concerning the?MRPS30?genomic region and the effects of hormonal and dietary exposures on postmenopausal breast cancer risk | mechanism | BC/OC research |
| MRPS30 | The 5p12 breast cancer susceptibility locus affects MRPS30 expression in estrogen-receptor positive tumors | 24388359 | The 5p12 risk allele affects MRPS30 expression in estrogen-responsive tumor cells after tumor initiation by a mechanism affecting chromatin availability | mechanism | BC/OC research |
| MRPS30 | Evidence that the 5p12 Variant rs10941679 confers susceptibility to estrogen-receptor-positive breast cancer through FGF10 and MRPS30 regulation. | 27640304 | 5p12 is mediated through coordinated activation of FGF10 and MRPS30, two candidate genes for breast cancer pathogenesis | mechanism | BC/OC research |
| MRPS30 | Integrative genomic analysis predicts causative cis-regulatory mechanisms of the breast cancer–associated genetic variant rs4415084 | 29351903 | MRPS30 encodes a member of the mitochondrial ribosomal proteins, implicating the role of risk SNP in modulating mitochondrial activities in breast cancer | mechanism | BC/OC research |
Survival analysis
Pathway
| Pathway Term | Reference DB | |
|---|---|---|
| MRPS30 | R-HSA-5368286 | Reactome |
| MRPS30 | R-HSA-5389840 | Reactome |
| MRPS30 | R-HSA-5419276 | Reactome |
| MRPS30 | Mitochondrial translation (Homo sapiens) | Wikipathway |