hsa-miR-130a
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| hsa-miR-130a | MicroRNA-130a inhibits cell proliferation, invasion and migration in human breast cancer by targeting the RAB5A | 25755726 | MiR-130a is an important tumor suppressor in breast cancer, and imply that miR-130a/RAB5A axis have potential as therapeutic targets for breast cancer | mechanism | BC/OC research |
| hsa-miR-130a | MiR-130a and MiR-374a Function as Novel Regulators of Cisplatin Resistance in Human Ovarian Cancer A2780 Cells | 26043084 | The deregulation of miR-374a and miR-130a may be involved in the development and regulation of cisplatin resistance in ovarian cancer cells; miR-130a may be achieved by regulating the MDR1 and PTEN gene expression | mechanism | BC/OC research |
| hsa-miR-130a | miR-130a Deregulates PTEN and Stimulates Tumor Growth | 28935812 | MiR-130a overexpression in human breast cancer cells promoted Akt phosphorylation, cell survival, and tumor growth;MiR-130a as an oncogenic miRNA that targets PTEN to drive malignant cell survival and tumor growth | mechanism | BC/OC research |
| hsa-miR-130a | microRNA-130a suppresses breast cancer cell migration and invasion by targeting FOSL1 and upregulating ZO-1 | 29384218 | MiR-130a directly targets FOSL1 and suppresses the inhibition of ZO-1, thus inhibiting cancer cell migration and invasion, in TNBCs | mechanism | BC/OC research |
| hsa-miR-130a | miR-130a and miR-145 reprogram Gr-1+CD11b+ myeloid cells and inhibit tumor metastasis through improved host immunity | 29973593 | MiR-130a targeted molecular networks including TGFβ and IGF1R pathways were correlated with higher tumor stages in cancer patients to enhance host antitumor immunity | mechanism | BC/OC research |
| hsa-miR-130a | The MYB/miR-130a/NDRG2 axis modulates tumor proliferation and metastatic potential in salivary adenoid cystic carcinoma | 30206227 | MYB/miR-130a/NDRG2 axis, which modulates proliferation and metastasis in SACC, provides promising targets for the treatment of SACC | mechanism | BC/OC research |
| hsa-miR-130a | MicroRNA-130a modulates a radiosensitivity of rectal cancer by targeting SOX4 | 31387015 | MiR-130a functions as a radiosensitizer in rectal cancer and reveals a potential therapeutic target and preoperative prognostic marker for radiotherapy | biomarker | BC/OC research |
| hsa-miR-130a | Molecular characterization of exosome-like vesicles from breast cancer cells | 24468161 | Comparing the miRNAs in MDA-Exo to MCF-Exo showed a higher expression of tumorigenic mir-130a in MDA-Exo. it has been shown that mir-130a contribute to tumorigenesis of colon cancer by regulating TGB-β/Smad signaling | mechanism | BCEXO research |
Survival analysis
Pathways
| Enriched Terms | Cross Refer. |
|---|---|
| Hematopoietic cell lineage | KEGG |
| RNA degradation | KEGG |
| Cytokine cytokine receptor interaction | KEGG |