hsa-miR-615-3p
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| hsa-miR-615-3p | miR-615-3p expression level in bone marrow is associated with tumor recurrence in hepatocellular carcinoma | 26137255 | MiR-615-3p in DTCs may play an important role in postoperative HCC recurrence, which suggests that?miR-615-3p?is a potential target molecule for regulating postoperative HCC recurrence | mechanism | BC/OC research |
| hsa-miR-615-3p | Molecular Pathways: Clinical Applications and Future Direction of Insulin-like Growth Factor-1 Receptor Pathway Blockade | 26429980 | A negative correlation between miR-615-3p levels and IGF2 has been identified in NSCLC specimens, with IGF2/IGFR1 interaction acting as a mediator of metastasis in several types of tumors | mechanism | BC/OC research |
| hsa-miR-615-3p | Plasma exosomal miRNAs-based prognosis in metastatic kidney cancer | 28969022 | Kaplan-Meier analysis confirmed the significant OS association of three miRs; miR-let-7i-5p (P=0.018, HR=0.49, 95% CI=0.21-0.84), miR-26a-1-3p (P=0.025, HR=0.43, 95% CI=0.10-0.84) and miR-615-3p (P=0.0007, HR=0.36, 95% CI=0.11-0.54) | biomarker | BC/OC research |
| hsa-miR-615-3p | miR-615-3p promotes proliferation and migration and inhibits apoptosis through its potential target CELF2 in gastric cancer | 29501762 | MiR-615-3p promotes gastric cancer proliferation and migration by suppressing CELF2 expression for the first time, providing clues for future clinical practices | mechanism | BC/OC research |
| hsa-miR-615-3p | MicroRNA 615-3p Inhibits the Tumor Growth and Metastasis of NSCLC via Inhibiting IGF2 | 29562959 | MiR-615-3p played important roles in the regulation of NSCLC growth and metastasis by targeting IGF2 | mechanism | BC/OC research |
| hsa-miR-615-3p | Identification of microRNA-615-3p as a novel tumor suppressor in non-small cell lung cancer | ?28454411 | MiR-615-3p functions as a tumor suppressor in NSCLC, and may be a novel potential molecular therapeutic target for patients with NSCLC;The results revealed that overexpressed miR-615-3p markedly inhibited cell proliferation and colony formation in the 3 NSCLC cell lines compared with the cells overexpressing the negative control sequence (NC). Additional investigation revealed that miR-615-3p overexpression significantly induced apoptosis and cell cycle arrest at the G1 phase in the A549, H1299 and H1650 cell lines compared with the cells overexpressing NC. Finally, ectopic expression of miR-615-3p was found to repress the cell migration and invasion of the 3 lung cancer cell lines | mechanism | BC/OC research |
Survival analysis
Pathways
| Enriched Terms | Cross Refer. |
|---|---|
| Galactose metabolism | KEGG |
| Steroid biosynthesis | KEGG |
| Lysine degradation | KEGG |
| Valine, leucine and isoleucine biosynthesis | KEGG |
| MicroRNAs in cancer | KEGG |