POU4F1
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| POU4F1 | AML1/ETO proteins control POU4F1/BRN3A expression and function in t(8;21) acute myeloid leukaemia | 20460523 | POU4F1/BRN3A?as a novel potential up-regulated AML1/ETO target gene whose dramatically high expression may co-operate with AML1/ETO in t(8;21) cells | mechanism | BC/OC research |
| POU4F1 | Genome-wide methylation screen in low-grade breast cancer identifies novel epigenetically altered genes as potential biomarkers for tumor diagnosis | 22930747 | In tumors, median methylation levels of BCAN, HOXD1, KCTD8, KLF11, NXPH1, POU4F1, SIM1, and TCF7L1 were ≥30% higher than in normal samples, representing potential biomarkers for tumor diagnosis | biomarker | BC/OC research |
| POU4F1 | DNA methylation in ductal carcinoma in situ of the breast | 23826974 | Eleven genes (BCAN, HOXD1, KCTD8, KLF11, NXPH1, PCDH10, POU4F1, RYR2, SIM1, TAC1, and?TCF7L1) were validated as being aberrantly methylated in DCIS and IDC compared with normal breast tissue | mechanism | BC/OC research |
| POU4F1 | POU4F1 is associated with t(8;21) acute myeloid leukemia and contributes directly to its unique transcriptional signature | ?20376082 | Among the most highly differentially expressed genes, half are known AML1/ETO targets, implying that the unique transcriptional signature of t(8;21) AML is, in part, attributable to?POU4F1?and not?AML1/ETO?itself. | mechanism | BC/OC research |
Survival analysis
Pathway
| Pathway Term | Reference DB | |
|---|---|---|
| POU4F1 | Regulation of TP53 Activity through Association with Co-factors (Homo sapiens) | Wikipathway |