IL1RAP
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| IL1RAP | Selective killing of candidate AML stem cells by antibody targeting of IL1RAP | 23479569 | IL1RAP is a promising new therapeutic target in AML | mechanism | BC/OC research |
| IL1RAP | Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia | 26261316 | Collectively, these results provide important evidence in support of IL1RAP as a target for antibody-based treatment of AML | mechanism | BC/OC research |
| IL1RAP | Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia | 26261316 | Critical evidence in support of a rapid clinical development of an antibody-based anti-IL1RAP therapy in AML | mechanism | BC/OC research |
| IL1RAP | SRSF10-mediated IL1RAP alternative splicing regulates cervical cancer oncogenesis via mIL1RAP-NF-κB-CD47 axis | 29429992 | SRSF10-mIL1RAP-CD47 axis could be an attractive therapeutic target for the treatment of cervical cancer | mechanism | BC/OC research |
| IL1RAP | IL1RAP potentiates multiple oncogenic signaling pathways in AML | 29773641 | Our study provides a new mechanistic basis for the efficacy of IL1RAP targeting in AML and reveals a novel role for this protein in the pathogenesis of the disease | mechanism | BC/OC research |
| IL1RAP | Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential | 29115712 | Presumably aid in targeting the primary cancer cells to specific metastatic sites | mechanism | BCEXO research |
Survival analysis
Pathway
| Pathway Term | Reference DB | |
|---|---|---|
| IL1RAP | R-HSA-449147 | Reactome |
| IL1RAP | hsa04060:Cytokine-cytokine receptor interaction | KEGG |
| IL1RAP | hsa04750:Inflammatory mediator regulation of TRP channels | KEGG |
| IL1RAP | R-HSA-446652 | Reactome |