hsa-miR-122
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| hsa-miR-122 | De novo sequencing of circulating miRNAs identifies novel markers predicting clinical outcome of locally advanced breast cancer | 22400902 | Certain miRNAs can serve as potential blood-based biomarkers for NCT response, and that miR-122 prevalence in the circulation predicts BC metastasis in early-stage patients | biomarker | BC/OC research |
| hsa-miR-122 | MiR-122 inhibits cell proliferation and tumorigenesis of breast cancer by targeting IGF1R | 23056576 | MiR-122 may serve as a novel therapeutic or diagnostic/prognostic-target for treating BC | biomarker | BC/OC research |
| hsa-miR-122 | MiR-122 inhibits cell proliferation and tumorigenesis of breast cancer by targeting IGF1R | 23056576 | MiR-122 functions as a tumor suppressor and plays an important role in inhibiting the tumorigenesis through targeting IGF1R and regulating PI3K/Akt/mTOR/p70S6K pathway | mechanism | BC/OC research |
| hsa-miR-122 | Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis | 25621950 | By modifying glucose utilization by recipient premetastatic niche cells, cancer-derived extracellular miR-122 is able to reprogram systemic energy metabolism to facilitate disease progression | biomarker | BC/OC research |
| hsa-miR-122 | Evaluation of miR-122 as a Serum Biomarker for Hepatotoxicity in Investigative Rat Toxicology Studies | 26123229 | Serum miR-122 levels can be utilized as a biomarker of hepatotoxicity in acute and subacute rat toxicology studies, and its performance can rival or exceed those of standard enzyme biomarkers such as the liver transaminases | biomarker | BC/OC research |
| hsa-miR-122 | Inhibition of breast cancer cell proliferation and tumorigenesis by long non-coding RNA RPPH1 down-regulation of miR-122 expression | 29200969 | Breast cancer progression can be promoted by directly targeting miR-122 through lncRNA RPPH1 | mechanism | BC/OC research |
| hsa-miR-122 | Breast-cancer-secreted hsa-miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis | 25621950 | Hsa-miR-122 suppresses glucose uptake by downregulating the glycolytic enzyme pyruvate kinase (PKM)to promote metastasis | mechanism | BCEXO research |
| hsa-miR-122 | Plasma exosome microRNAs are indicative of breast cancer | 27608715 | Based on the selective enrichment and absolute abundance, we identified miR-1246, miR-122, miR-21, and let-7a as candidate exosome microRNAs that may serve as biomarkers indicative of breast cancer | biomarker | BCEXO research |
Survival analysis
Pathways
| Enriched Terms | Cross Refer. |
|---|---|
| Thyroid hormone signaling pathway | KEGG |
| Pathways in cancer | KEGG |
| Insulin signaling pathway | KEGG |
| Prostate cancer | KEGG |
| Signaling pathways regulating pluripotency of stem cells | KEGG |
| AMPK signaling pathway | KEGG |
| Cell cycle | KEGG |
| Melanoma | KEGG |
| Lysine degradation | KEGG |
| Non-small cell lung cancer | KEGG |