Validation

Gene Symbol Curated Descriptions Cell Lines Isolations Validations Control-case Tumor Stage & Subtypesort descending Clinical Use PMID
hsa-miR-30a Target gene prediction and pathway analysis showed the involvement of miR-100, miR-222, and miR-30a in pathways implicated in cancer pathogenesis, membrane vesiculation and therapy failure，the transmition of chemoresistance by a horizontal transfer of miRNAs MCF7 ultracentrifugation transmission electron microscopy drug resistance 24740415
hsa-miR-31 Hsa-miR-31 modulates MCF-7 cells growth by specially targeting the histone deacetylase 2 MCF7 centrifugation transmission electron microscopy 30916359
hsa-miR-328 MDA-Exo also contains significant amounts of hsa-miR-328,which has been shown to target CD44,reduce cell adhesion,enhance cell migration and regulate capillary structure formation MCF7,MDA-MB231 ultracentrifugation electron microscopy metastasis 24468161
hsa-miR-34a MCF-Exo also contains mir-34a, which regulates several genes including p53 MCF7,MDA-MB231 ultracentrifugation electron microscopy 24468161
hsa-miR-720 Hsa-miR-720 is characterized by excessive release from breast cancer cells while retaining relatively low concentrations of miRNA in the cells and could be used to detect the presence of malignant cells in the body MDA-MB-231,MCF7 centrifugation negative-staining electron microscopy 22772984
ITGB1 Presumably aid in targeting the primary cancer cells to specific metastatic sites 4T1 ultracentrifugation transmission electron microscopy metastasis 29115712
KRT14 Presumably aid in targeting the primary cancer cells to specific metastatic sites 4T1 ultracentrifugation transmission electron microscopy metastasis 29115712
KISS1R Stemness markers and enhance proliferation,migration and invasion abilities of neighboring cells MDA-MB-231,T47D centrifugationand filtration transmission electron microscopy metastasis 26528758
FGFR2 Presumably aid in targeting the primary cancer cells to specific metastatic sites 4T1 ultracentrifugation transmission electron microscopy metastasis 29115712
IL1RAP Presumably aid in targeting the primary cancer cells to specific metastatic sites 4T1 ultracentrifugation transmission electron microscopy metastasis 29115712

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