Validation
Gene Symbol | Curated Descriptions | Cell Lines | Isolations | Validations | Control-case | Tumor Stage & Subtype | Clinical Use | PMID |
---|---|---|---|---|---|---|---|---|
EPCAM | Tumour-derived exosomes interfere with the tumour-specific function of immune cells and constitute an additional mechanism how tumours escape from immune surveillance | BT474 | ultracentrifugation | electron microscopy | 21293856 | |||
ERBB2 | Tumour-derived exosomes interfere with the tumour-specific function of immune cells and constitute an additional mechanism how tumours escape from immune surveillance | BT474 | ultracentrifugation | electron microscopy | 21293856 | |||
FGFR2 | Presumably aid in targeting the primary cancer cells to specific metastatic sites | 4T1 | ultracentrifugation | transmission electron microscopy | metastasis | 29115712 | ||
FGFR3 | Presumably aid in targeting the primary cancer cells to specific metastatic sites | 4T1 | ultracentrifugation | transmission electron microscopy | metastasis | 29115712 | ||
FIBP | Presumably aid in targeting the primary cancer cells to specific metastatic sites | 4T1 | ultracentrifugation | transmission electron microscopy | metastasis | 29115712 | ||
FRS2 | Presumably aid in targeting the primary cancer cells to specific metastatic sites | 4T1 | ultracentrifugation | transmission electron microscopy | metastasis | 29115712 | ||
GSTP1 | Affecting drug metabolism---Anthracycline/taxane-based neoadjuvant chemotherapy | MCF7 | ultracentrifugation | transmission electron microscopy | drug resistance | 28438694 | ||
hsa-miR-100 | Target gene prediction and pathway analysis showed the involvement of miR-100, miR-222, and miR-30a in pathways implicated in cancer pathogenesis, membrane vesiculation and therapy failure,the transmition of chemoresistance by a horizontal transfer of miRNAs | MCF7 | ultracentrifugation | transmission electron microscopy | drug resistance | 24740415 | ||
hsa-miR-105 | Hsa-miR-105 has significantly up-regulated and has been extensively implicated in cancer progression | MDA-MB-231 | ultracentrifugation | electron microscopy | metastasis | 24735924 | ||
hsa-miR-106b | The mir-106b is found in higher levels in MCF-Eox as well, which can promote breast cancer invasion and metastasis by targeting BRMS1 and RB | MCF7,MDA-MB231 | ultracentrifugation | electron microscopy | 24468161 |