hsa-miR-1246
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| hsa-miR-1246 | microRNA-1246 Is an Exosomal Biomarker for Aggressive Prostate Cancer | 29437039 | Ex-miR-1246 expression correlated with increasing pathologic grade, positive metastasis, and poor prognosis | biomarker | BC/OC research |
| hsa-miR-1246 | microRNA-1246 Is an Exosomal Biomarker for Aggressive Prostate Cancer | 29437039 | Overexpression of miR-1246 in a prostate cancer cell line significantly inhibited xenograft tumor growth in vivo and increased apoptosis and decreased proliferation, invasiveness, and migration in vitro miR-1246 inhibited N-cadherin and vimentin activities, thereby inhibiting epithelial-mesenchymal transition | mechanism | BC/OC research |
| hsa-miR-1246 | Exosome-packaged miR-1246 contributes to bystander DNA damage by targeting LIG4. | 30038324 | MiR-1246 packaged in exosomes could act as a transfer messenger and contribute to DNA damage by directly repressing the LIG4 gene | mechanism | BC/OC research |
| hsa-miR-1246 | In Situ Detection of Plasma Exosomal MicroRNA-1246 for Breast Cancer Diagnostics by a Au Nanoflare Probe | 30350935 | Using plasma miR-1246 level detected by our assay as a marker, we differentiated 46 breast cancer patients from 28 healthy controls with 100% sensitivity and 92.9% specificity at the best cutoff | biomarker | BC/OC research |
| hsa-miR-1246 | Exosomal MicroRNA hsa-miR-1246 Promotes Cell Proliferation,Invasion and Drug Resistance by Targeting CCNG2 in Breast Cancer | 29216623 | Hsa-miR-1246 promotes cell proliferation,invasion and drug resistance by targeting CCNG2 in breast cancer | mechanism | BCEXO research |
| hsa-miR-1246 | Plasma exosome microRNAs are indicative of breast cancer | 27608715 | Based on the selective enrichment and absolute abundance, we identified miR-1246, miR-122, miR-21, and let-7a as candidate exosome microRNAs that may serve as biomarkers indicative of breast cancer | biomarker | BCEXO research |