RN7SL1
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| RN7SL1 | Exosomal proteins as potential markers of tumor diagnosis | 29282096 | Breast cancer cells can stimulate stromal fibroblasts to produce stromal exosomes, which contain unshielded endogenous RNA (RN7SL1), via triggering NOTCH-MYC pathways. Delivering unshielded RN7SL1 to breast cancer cells facilitates cancer growth, metastasis, and therapy resistance through retinoic acid-inducible gene I (RIG-I) signaling | mechanism | BC/OC research |
| RN7SL1 | The decade of exosomal long RNA species: an emerging cancer antagonist | 29558960 | Assessments of the blood samples of breast cancer patients revealed the presence of unshielded RN7SL1 in exosomes. Thus, exosomal content can be utilized to identify patients with more aggressive cancers by detecting exosome-binding RN7SL1 | mechanism | BC/OC research |
| RN7SL1 | Exosomes From The Tumor Microenvironment Promote Breast Cancer Progression And Therapy Resistance Through Unshielded Non-Coding Rna | Link | Unshielded stromal RN7SL1 in exosomes, which is also found in cancer patients, is transferred to breast cancer cells to stimulate the pattern recognition receptor RIG-I and activate STAT1-dependent anti-viral signaling | mechanism | BC/OC research |
| RN7SL1 | Exosome RNA Unshielding Couples Stromal Activation to Pattern Recognition Receptor Signaling in Cancer | 28709002 | Unshielded RN7SL1 in exosomes acts as a DAMP and activates breast cancer RIG-I to promote aggressive features of cancer | mechanism | BCEXO research |