hsa-let-7a
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| hsa-let-7a | MicroRNA let-7a suppresses breast cancer cell migration and invasion through downregulation of C-C chemokine receptor type 7 | 22251626 | Targeting of CCL21-CCR7 signaling is a valid approach for breast cancer therapy and that let-7a directly binds to the 3'UTR of CCR7 and blocks its protein expression, thereby suppressing migration and invasion of human breast cancer cells | mechanism | BC/OC research |
| hsa-let-7a | Let-7a inhibits growth and migration of breast cancer cells by targeting HMGA1 | 25846193 | Let-7a plays an important role as a tumor suppressor gene by targeting HMGA1, which may open novel perspectives for clinical treatments against breast cancer | mechanism | BC/OC research |
| hsa-let-7a | Expression of tumor suppressors miR-195 and let-7a as potential biomarkers of invasive breast cancer | 29995098 | MiR-195 and let-7a can be used as a non-invasive biomarker for breast cancer detection | biomarker | BC/OC research |
| hsa-let-7a | Role of let-7 family microRNA in breast cancer | 30159414 | This article will provide the in-depth insight into the biology of let-7 miRNA and its role in the breast cancer progression | mechanism | BC/OC research |
| hsa-let-7a | Plasma miR-21, miR-155, miR-10b, and Let-7a as the potential biomarkers for the monitoring of breast cancer patient | 30568292 | Hsa-let-7a might be considered as a respectable diagnostic tool for monitoring of breast cancer patients | biomarker | BC/OC research |
| hsa-let-7a | Robust expression of tumor suppressor miRNA’s let-7 and miR-195 detected in plasma of Saudi female breast cancer patients | 29183284 | In order to facilitate earlier detection of breast cancer, blood based screening of hsa-miR-195 and let-7 may be beneficial in a female patient cohort | mechanism | BC/OC research |
| hsa-let-7a | Plasma exosome microRNAs are indicative of breast cancer | 27608715 | Based on the selective enrichment and absolute abundance, we identified miR-1246, miR-122, miR-21, and let-7a as candidate exosome microRNAs that may serve as biomarkers indicative of breast cancer | biomarker | BCEXO research |
Survival analysis
Pathways
| Enriched Terms | Cross Refer. |
|---|---|
| Bladder cancer | KEGG |
| Colorectal cancer | KEGG |
| Pathways in cancer | KEGG |
| Endocytosis | KEGG |
| Transcriptional misregulation in cancer | KEGG |
| Arrhythmogenic right ventricular cardiomyopathy | KEGG |
| MAPK signaling pathway | KEGG |
| Shigellosis | KEGG |
| FoxO signaling pathway | KEGG |
| Salmonella infection | KEGG |