CCKBR
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| CCKBR | A single nucleotide polymorphism of the cholecystokinin-B receptor predicts risk for pancreatic cancer | 22277584 | Single nucleotide polymorphism (SNP) in the cholecystokinin B receptor (CCKBR) gene predicts survival and risk of pancreatic cancer | biomarker | BC/OC research |
| CCKBR | A single nucleotide polymorphism of the cholecystokinin-B receptor predicts risk for pancreatic cancer | 22277584 | Growth of human pancreatic cancer is stimulated by gastrin through the CCKBR and an alternatively spliced isoform of the CCKBR gene called CCKCR | mechanism | BC/OC research |
| CCKBR | MiR-148a regulates the growth and apoptosis in pancreatic cancer by targeting CCKBR and Bcl-2 | 23975374 | MiR-148a's targeting of CCKBR and Bcl-2 in the regulation of pancreatic cancer growth and apoptosis | mechanism | BC/OC research |
| CCKBR | Heterogeneous expression of cholecystokinin and gastrin receptor in stomach and pancreatic cancer: An immunohistochemical study | 27072272 | Significantly higher expression of CCKAR and down regulation of CCKBR in PC as compared to control while CCKBR/GR was detected in majority of SC samples | mechanism | BC/OC research |
| CCKBR | Expression of the Cholecystokinin-B Receptor in Neoplastic Gastric Cells | 28980157 | All eight NENs expressed CCKBR and neuroendocrine markers in a majority of tumor cells | mechanism | BC/OC research |
| CCKBR | Low serum gastrin associated with ER+ breast cancer development via inactivation of CCKBR/ERK/P65 signaling | 30115027 | CCKBR/ERK/P65 signaling function is generally tumor suppressive in ER+ BC, indicating therapies should focus on restoring, not inhibiting, CCKBR/ERK/P65 pathway activity | mechanism | BC/OC research |
Survival analysis
Pathway
| Pathway Term | Reference DB | |
|---|---|---|
| CCKBR | R-HSA-375276 | Reactome |
| CCKBR | R-HSA-416476 | Reactome |
| CCKBR | R-HSA-881907 | Reactome |
| CCKBR | hsa04020:Calcium signaling pathway | KEGG |
| CCKBR | hsa04080:Neuroactive ligand-receptor interaction | KEGG |
| CCKBR | hsa04971:Gastric acid secretion | KEGG |
| CCKBR | GPCRs, Other (Homo sapiens) | Wikipathway |
| CCKBR | GPCR downstream signaling (Homo sapiens) | Wikipathway |
| CCKBR | GPCR ligand binding (Homo sapiens) | Wikipathway |
| CCKBR | Peptide GPCRs (Homo sapiens) | Wikipathway |