hsa-miR-128
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| hsa-miR-128 | Reduced miR-128 in breast tumor-initiating cells induces chemotherapeutic resistance via Bmi-1 and ABCC5 | 21953503 | Reduction in miR-128 leading to Bmi-1 and ABCC5 overexpression is a stem cell-like feature of BT-ICs, which contributes to chemotherapeutic resistance in breast cancers. Ectopic expression of miR-128 sensitizes BT-ICs to the proapoptotic and DNA-damaging effects of doxorubicin, indicating therapeutic potential | mechanism | BC/OC research |
| hsa-miR-128 | Loss of SNAIL regulated miR-128-2 on chromosome 3p22.3 targets multiple stem cell factors to promote transformation of mammary epithelial cells | 23019226 | In summary, we have identified a novel TGF-β/SNAIL/miR-128 axis that provides a new avenue to understand the basis for oncogenic transformation of mammary epithelial cells | mechanism | BC/OC research |
| hsa-miR-128 | miR-128 and its target genes in tumorigenesis and metastasis | 23958464 | Aberrant expression of miR-128 has been detected in many types of human tumors and its validated target genes are involved in cancer-related biological processes such as cell proliferation, differentiation and apoptosis | mechanism | BC/OC research |
| hsa-miR-128 | miR-128 and miR-149 enhance the chemosensitivity of temozolomide by Rap1B-mediated cytoskeletal remodeling in glioblastoma | 25017996 | The expression of miR-128 and miR-149 was downregulated in glioblastoma, and their overexpression inhibited the invasion of glioblastoma cells by targeting Rap1B-mediated cytoskeletal and related molecular alterations | mechanism | BC/OC research |
| hsa-miR-128 | MiR-128 regulation of glucose metabolism and cell proliferation in triple-negative breast cancer | 29116653 | MiR-128 might be a prognostic marker and possible molecular target for therapy in patients with TNBC | biomarker | BC/OC research |
| hsa-miR-128 | MiR-128 regulation of glucose metabolism and cell proliferation in triple-negative breast cancer | 29116653 | MiR-128 targeting inhibition of the insulin receptor and insulin receptor substrate 1 | mechanism | BC/OC research |
| hsa-miR-128 | Shikonin Inhibits the Proliferation of Human Breast Cancer Cells by Reducing Tumor-Derived Exosomes | 27322220 | Hsa-miR-128 negatively regulates the level of Bax in MCF7recipient cells and inhibits cell proliferation | mechanism | BCEXO research |
Survival analysis
Pathways
| Enriched Terms | Cross Refer. |
|---|---|
| Pathways in cancer | KEGG |
| Non small cell lung cancer | KEGG |
| Small cell lung cancer | KEGG |
| Chronic myeloid leukemia | KEGG |
| Bladder cancer | KEGG |
| Melanoma | KEGG |
| Prostate cancer | KEGG |
| Glioma | KEGG |
| Pancreatic cancer | KEGG |
| PPAR signaling pathway | KEGG |