hsa-miR-486-5p

Submitted by Anonymous on Wed, 10/30/2019 - 22:16

Pubmed

Gene symble	Title	PMID	Curated descirption	Category	Literature category
hsa-miR-486-5p	MicroRNA-486-5p targeting PIM-1 suppresses cell proliferation in breast cancer cells	25104088	MiR-486-5p/PIM-1 axis provides insight into the pathogenesis of BC and might be therapeutic targets for prevention or treatment of BC	mechanism	BC/OC research
hsa-miR-486-5p	Down-regulated miR-486-5p acts as a tumor suppressor in breast cancer patients by targeting the metastatic mediator ICAM-1	27882172	MiR-486-5p decreases the metastatic property of ICAM-1. In addition, miR-486-5p acts as a tumor suppressor in BC;increasing the levels of the under-expressed miR-486-5p in TNBC tissues can be a possible therapeutic approach for halting BC progression	mechanism	BC/OC research
hsa-miR-486-5p	S-Adenosylmethionine regulates apoptosis and autophagy in MCF-7 breast cancer cells through the modulation of specific microRNAs	30533999	MiR-486-5p inhibitor induces autophagy and enhances AdoMet-induced autophagic process by increasing PTEN expression and by inhibiting AKT signaling	mechanism	BC/OC research
hsa-miR-486-5p	MiR-486-5p prevents migration, invasion and EMT by regulating Smad2 in breast cancer	Link	MiR-486-5p may represent as a new treatment target and prognostic marker for breast cancer	biomarker	BC/OC research
hsa-miR-486-5p	Differential expression of exosomal miRNAs between breast cancer patients with and without recurrence	29050253	Of 384 miRNAs, three miRNAs (miR-338-3p, miR-340-5p, and miR-124-3p) were significantly upregulated and eight (miR-29b-3p, miR-20b-5p, miR-17-5p, miR-130a-3p, miR-18a-5p, miR-195-5p, miR-486-5p, and miR-93-5p) were significantly downregulated in the patients with recurrence	biomarker	BCEXO research

Survival analysis

Pathways

Enriched Terms	Cross Refer.
Arrhythmogenic right ventricular cardiomyopathy	KEGG