RIPK1
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| RIPK1 | RIPK1 Binds MCU to Mediate Induction of Mitochondrial Ca2+ Uptake and Promotes Colorectal Oncogenesis | 29531160 | These findings identify the RIPK1-MCU pathway as a promising target to treat colorectal cancer. | mechanism | BC/OC research |
| RIPK1 | Differential involvement of TAK1, RIPK1 and NF-κB signaling in Smac mimetic-induced cell death in breast cancer cells | 30391931 | TAK1, receptor-interacting kinase 1 (RIPK1) as well as canonical and non-canonical NF-κB signaling are differentially involved in SM-induced cell death in breast cancer cells. These findings contribute to a better understanding of SM-induced signaling pathways | mechanism | BC/OC research |
| RIPK1 | FKBP12 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation | 31028177 | FKBP12 may target RIPK1 and RIPK3 to mediate necroptosis in vitro and in vivo Collectively, our data demonstrate that FKBP12 could be a potential therapeutic target for the clinical treatment of necroptosis-associated diseases | mechanism | BC/OC research |
| RIPK1 | Discovery of potent necroptosis inhibitors targeting RIPK1 kinase activity for the treatment of inflammatory disorder and cancer metastasis | 31235688 | PK68 is a potent and selective inhibitor of RIPK1 and also highlights its great potential for use in the treatment of inflammatory disorders and cancer metastasis | mechanism | BC/OC research |
Survival analysis
Pathway
| Pathway Term | Reference DB | |
|---|---|---|
| RIPK1 | TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway (Homo sapiens) | Wikipathway |
| RIPK1 | Apoptosis (Homo sapiens) | Wikipathway |
| RIPK1 | Nanoparticle triggered regulated necrosis (Homo sapiens) | Wikipathway |
| RIPK1 | Integrated Lung Cancer Pathway (Homo sapiens) | Wikipathway |
| RIPK1 | TNF alpha Signaling Pathway (Homo sapiens) | Wikipathway |
| RIPK1 | Apoptosis Modulation and Signaling (Homo sapiens) | Wikipathway |
| RIPK1 | hsa05160:Hepatitis C | KEGG |
| RIPK1 | Regulation of toll-like receptor signaling pathway (Homo sapiens) | Wikipathway |
| RIPK1 | MyD88-independent TLR3/TLR4 cascade (Homo sapiens) | Wikipathway |
| RIPK1 | DDX58/IFIH1-mediated induction of interferon-alpha/beta (Homo sapiens) | Wikipathway |