PSMC5
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| PSMC5 | A network-based, integrative study to identify core biological pathways that drive breast cancer clinical subtypes | 22343619 | Several seed genes for the ER network, including APPBP2, ASH2L, BAG4, CCND1, CLTC, DDX5, DEDD, EPN3, GPAA1, PHB, PRKAR1A, PRKDC, PSMC5, PTK2, RPS6KB1, SPOP, and YWHAZ were not significantly over- or under-expressed in ER+ cancers relative to other subtypes but showed copy number abnormalities | mechanism | BC/OC research |
| PSMC5 | Radiosensitizing effect of PSMC5, a 19S proteasome ATPase, in H460 lung cancer cells | 26592665 | PSMC5 facilitates the damaging effects of radiation in radiation-responsive H460 cancer cells and therefore may serve as a prognostic indicator for radiotherapy and molecular targeted therapy in lung cancer patients | mechanism | BC/OC research |
| PSMC5 | Using Quantitative Seroproteomics to Identify Antibody Biomarkers in Pancreatic Cancer | 26842750 | We further interrogated these proteins in over 80 GVAX-treated patients' pancreases and uniformly found a significant increase in the expression of MYPT1, PSMC5, and TFRC in neoplastic compared with non-neoplastic pancreatic ductal epithelium | mechanism | BC/OC research |
| PSMC5 | Circulating protein and antibody biomarker for personalized cancer immunotherapy | 27532021 | Using this assay, several new tumor antigens (MYPT1, PSMC5 and TRFR) were identified that were found to have significantly different expression in tumors compared with normal tissue | mechanism | BC/OC research |
Survival analysis
Pathway
| Pathway Term | Reference DB | |
|---|---|---|
| PSMC5 | Regulation of mitotic cell cycle (Homo sapiens) | Wikipathway |
| PSMC5 | Mitotic Metaphase and Anaphase (Homo sapiens) | Wikipathway |
| PSMC5 | Degradation of beta-catenin by the destruction complex (Homo sapiens) | Wikipathway |
| PSMC5 | M/G1 Transition (Homo sapiens) | Wikipathway |
| PSMC5 | Pregnane X Receptor pathway (Homo sapiens) | Wikipathway |
| PSMC5 | MAPK6/MAPK4 signaling (Homo sapiens) | Wikipathway |
| PSMC5 | Hedgehog 'on' state (Homo sapiens) | Wikipathway |
| PSMC5 | Hedgehog 'off' state (Homo sapiens) | Wikipathway |
| PSMC5 | TNFR2 non-canonical NF-kB pathway (Homo sapiens) | Wikipathway |
| PSMC5 | Transcriptional regulation by RUNX3 (Homo sapiens) | Wikipathway |