FZD5
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| FZD5 | Expression and regulation of WNT5A and WNT5B in human cancer: Up-regulation of WNT5A by TNFα in MKN45 cells and up-regulation of WNT5B by β-estradiol in MCF-7 cells | 12165812 | Up-regulation of WNT5A and WNT5B in several types of human cancer expressing FZD5 might lead to more malignant phenotype through activation of the β-catenin - TCF pathway | mechanism | BC/OC research |
| FZD5 | Microrna-224 inhibits proliferation and migration of breast cancer cells by down-regulating fizzled 5 expression | 27323393 | MiR-224 inhibited cell proliferation and migration by targeting FZD5 and inhibiting WNT/β-catenin signaling in breast cancer | mechanism | BC/OC research |
| FZD5 | MicroRNA-671-3p inhibits the development of breast cancer: A study based on in vitro experiments, in-house quantitative polymerase chain reaction and bioinformatics analysis | 29620195 | WNT3A, CCND2, SFRP1, PRICKLE2, FZD5 and FZD4 were markedly downregulated in BC, suggesting that they may function as tumor suppressor genes in this tumor | mechanism | BC/OC research |
| FZD5 | Role of WNT5A receptors FZD5 and RYK in prostate cancer cells | 29930766 | WNT5A/FZD5 and WNT5A/RYK signaling are both involved in mediating the pro-apoptotic and anti-proliferative effects of WNT5A in prostate cancer | mechanism | BC/OC research |
Survival analysis
Pathway
| Pathway Term | Reference DB | |
|---|---|---|
| FZD5 | ESC Pluripotency Pathways (Homo sapiens) | Wikipathway |
| FZD5 | GPCR ligand binding (Homo sapiens) | Wikipathway |
| FZD5 | Mesodermal Commitment Pathway (Homo sapiens) | Wikipathway |
| FZD5 | Ectoderm Differentiation (Homo sapiens) | Wikipathway |
| FZD5 | TCF dependent signaling in response to WNT (Homo sapiens) | Wikipathway |
| FZD5 | Beta-catenin independent WNT signaling (Homo sapiens) | Wikipathway |
| FZD5 | Association Between Physico-Chemical Features and Toxicity Associated Pathways (Homo sapiens) | Wikipathway |
| FZD5 | Breast cancer pathway (Homo sapiens) | Wikipathway |
| FZD5 | LncRNA involvement in canonical Wnt signaling and colorectal cancer (Homo sapiens) | Wikipathway |
| FZD5 | Epithelial to mesenchymal transition in colorectal cancer (Homo sapiens) | Wikipathway |