hsa-miR-155
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| hsa-miR-155 | MicroRNA-155 Regulates Cell Survival, Growth, and Chemosensitivity by Targeting FOXO3a in Breast Cancer | 27825093 | MiR-155 is a critical therapeutic target in breast cancer. | biomarker | BC/OC research |
| hsa-miR-155 | MicroRNA-155 Regulates Cell Survival, Growth, and Chemosensitivity by Targeting FOXO3a in Breast Cancer | 27825093 | The critical role of miR-155 in regulation of cell survival and chemosensitivity through down-regulation of FOXO3a in breast cancer. Ectopic expression of miR-155 induces cell survival and chemoresistance to multiple agents, whereas knockdown of miR-155 renders cells to apoptosis and enhances chemosensitivity. | mechanism | BC/OC research |
| hsa-miR-155 | MicroRNA-155, induced by FOXP3 through transcriptional repression of BRCA1, is associated with tumor initiation in human breast cancer | 28562349 | A transcriptional axis of FOXP3-BRCA1-miR-155 in breast cancer cells and show that plasma miR-155 may serve as a non-invasive biomarker for detection of early stage breast cancer. | biomarker | BC/OC research |
| hsa-miR-155 | MicroRNA-155, induced by FOXP3 through transcriptional repression of BRCA1, is associated with tumor initiation in human breast cancer | 28562349 | There was a positive correlation between expression of FOXP3 and miR-155 in breast cancer cell lines and primary breast cancers. In breast cancer cells, FOXP3 induced miR-155 through transcriptional repression of BRCA1. | mechanism | BC/OC research |
| hsa-miR-155 | Cancer Exosomes Perform Cell-Independent MicroRNA Biogenesis and Promote Tumorigenesis | 25446899 | Hsa-miR-155 has significantly up-regulated and has been extensively implicated in cancer progression | mechanism | BCEXO research |
| hsa-miR-155 | Presence of Circulating hsa-miR-145, hsa-miR-155, and hsa-miR-382 in Exosomes Isolated from Serum of Breast Cancer Patients and Healthy Donors | 30891102 | Our study showed that serum-circulating miR-145, miR-155, and miR-382 are present in exosomes. These miRNAs were previously proposed as noninvasive biomarkers to distinguish between BC patients and healthy individuals | biomarker | BCEXO research |
| hsa-miR-155 | miR-155 promotes macroscopic tumor formation yet inhibits tumor dissemination from mammary fat pads to the lung by preventing EMT. | 21460854 | The location of tumor cells overexpressing miR-155 is a critical factor: in mammary fat pads miR-155 prevents tumor dissemination; whereas in the lung miR-155 apparently maintains the epithelial phenotype of tumor cells that is critical for macroscopic tumor formation. | biomarker | BC/OC research |
| hsa-miR-155 | miR-155 promotes macroscopic tumor formation yet inhibits tumor dissemination from mammary fat pads to the lung by preventing EMT. | 21460854 | Stable expression of miR-155 in 4T1 breast tumor cells reduces significantly the aggressiveness of tumor cell dissemination as a result of preventing epithelial-to-mesenchymal transition (EMT) of tumor cells in vivo. Further, miR-155 directly suppresses the expression of the transcription factor TCF4, which is an important regulator of EMT. However, when tumor cells are injected directly into the bloodstream, miR-155 remarkably promotes macroscopic tumor formation in the lung. | mechanism | BC/OC research |
Survival analysis
Pathways
| Enriched Terms | Cross Refer. |
|---|---|
| RNA transport | KEGG |
| TGF-beta signaling pathway | KEGG |
| Chronic myeloid leukemia | KEGG |
| Malaria | KEGG |
| Prolactin signaling pathway | KEGG |
| Glioma | KEGG |
| Other glycan degradation | KEGG |
| Endometrial cancer | KEGG |
| Small cell lung cancer | KEGG |
| Fatty acid metabolism | KEGG |