HLA-DQA1
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| HLA-DQA1 | Contribution of the TP53, OGG1, CHRNA3, and HLA-DQA1 genes to the risk for lung squamous cell carcinoma | 21623257 | Genotypes for two DNA repair genes, TP53 and OGG1, showed significant associations with SQC risk (p < 0.05), and those for two GWAS genes, CHRNA3 and HLA-DQA1, showed significant associations with SQC risk (P < 0.05) with odds ratios between 1.65 (95% confidence interval = 1.06-2.57 for OGG1) and 2.57 (95% confidence interval = 1.03-6.87 for CHRNA3) | mechanism | BC/OC research |
| HLA-DQA1 | HLA-DRB1,-DQA1 and -DQB1 allele and haplotype frequencies in female patients with early onset breast cancer | 21720852 | HLA-DQA1*0301 allele is mainly associated with increased risk of breast cancer including early-onset of the disease. HLA-DQA1*0505 and HLA-DRB1*1301 are involved in protection. We conclude that specific alleles of HLA class II influence breast cancer risk | mechanism | BC/OC research |
| HLA-DQA1 | Association between HLA-DQA1, HLA-DQB1 and oral cancer | 21943816 | Both HLA-DQA1* and HLA-DQB1* allele frequencies in oral cancer patients revealed no significant difference from those of control groups | mechanism | BC/OC research |
| HLA-DQA1 | HLA-DQA1 & DQB1 variants associated with hepatitis B virus-related chronic hepatitis, cirrhosis & hepatocellular carcinoma | 30168489 | Our results revealed HLA-DQA1*0101/2/4 - DQA1*0103 - DQB1*0302/3 and DQB1*0601 as protective and DQB1*0402 as risk alleles. The study suggests that various subtypes of HLA-DQA1 and DQB1 are associated with both HBV clearance and development of chronic HBV infections | mechanism | BC/OC research |
| HLA-DQA1 | High expression of HLA-DQA1 predicts poor outcome in patients with esophageal squamous cell carcinoma in Northern China | 30813145 | HLA-DQA1 plays an important role in ESCC progression and may be a biomarker for ESCC diagnosis and prognosis, as well as a potential target for the treatment of patients with ESCC | mechanism | BC/OC research |
Survival analysis
Pathway
| Pathway Term | Reference DB | |
|---|---|---|
| HLA-DQA1 | Ebola Virus Pathway on Host (Homo sapiens) | Wikipathway |
| HLA-DQA1 | hsa05320:Autoimmune thyroid disease | KEGG |
| HLA-DQA1 | hsa05321:Inflammatory bowel disease (IBD) | KEGG |
| HLA-DQA1 | hsa05322:Systemic lupus erythematosus | KEGG |
| HLA-DQA1 | hsa05323:Rheumatoid arthritis | KEGG |
| HLA-DQA1 | hsa05330:Allograft rejection | KEGG |
| HLA-DQA1 | hsa05416:Viral myocarditis | KEGG |
| HLA-DQA1 | hsa05332:Graft-versus-host disease | KEGG |
| HLA-DQA1 | Vitamin D Receptor Pathway (Homo sapiens) | Wikipathway |
| HLA-DQA1 | Allograft Rejection (Homo sapiens) | Wikipathway |