hsa-miR-4443
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| hsa-miR-4443 | miR-4443 Participates in the Malignancy of Breast Cancer | 27504971 | MiR-4443 induced malignancy of breast cancer mainly in chemo-resistance aspect for the very first time, providing a novel biomarker in breast cancer diagnosis and therapy | biomarker | BC/OC research |
| hsa-miR-4443 | Leptin and insulin up-regulate miR-4443 to suppress NCOA1 and TRAF4, and decrease the invasiveness of human colon cancer cells | 27842582 | MiR-4443 acts in a tumor-suppressive manner by down-regulating TRAF4 and NCOA1 downstream of MEK-C/EBP-mediated leptin and insulin signaling, and that insulin and/or leptin resistance (e.g. in obesity) may suppress this pathway and increase the risk of metastatic CRC | mechanism | BC/OC research |
| hsa-miR-4443 | MicroRNA-4443 Causes CD4+ T Cells Dysfunction by Targeting TNFR-Associated Factor 4 in Graves’ Disease | 29163513 | The increased expression of miR-4443 induced CD4+ T cells dysfunction by targeting TRAF4, which may cause GD | mechanism | BC/OC research |
| hsa-miR-4443 | Downregulation of miR-4443 and miR-5195-3p in ovarian cancer tissue contributes to metastasis and tumorigenesis | 30810880 | Further investigation can help to suggest miR-4443 and miR-5195-3p as diagnostic biomarkers or therapeutic targets in OC | biomarker | BC/OC research |
| hsa-miR-4443 | Downregulation of miR-4443 and miR-5195-3p in ovarian cancer tissue contributes to metastasis and tumorigenesis | 30810880 | MiR-4443 and miR-5195-3p may contribute to suppressing tumor, so that decrease in their expression is associated with increased cell proliferation and invasion | mechanism | BC/OC research |
| hsa-miR-4443 | CircASS1 suppressed the invasion and metastasis ability of breast cancer cell line by targeting gene ASS1 and harboring miR-4443 | Link | CircASS1 suppresses invasion and migration capacity of BC cells by increasing expression of ASS1 and circASS1 could harbor miR-4443, suggesting that circASS1 could be a potential target in BC treatment and a prospective prognostic biological marker in BC. | mechanism | BC/OC research |
Survival analysis
Pathways
| Enriched Terms | Cross Refer. |
|---|---|
| Allograft rejection | KEGG |
| Autoimmune thyroid disease | KEGG |
| Herpes simplex infection | KEGG |
| Phagosome | KEGG |