hsa-miR-638
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| hsa-miR-638 | Downregulation of miR-638 promotes progression of breast cancer and is associated with prognosis of breast cancer patients | 30349320 | The miR-638 could be considered as an independent prognostic factor for the patients (HR =0.321, 95% CI =0.117–0.882, P=0.027) | biomarker | BC/OC research |
| hsa-miR-638 | Downregulation of miR-638 promotes progression of breast cancer and is associated with prognosis of breast cancer patients | 30349320 | Downregulation of miR-638 was capable of promoting cell proliferation, migration, and invasion in MDA-MB-231 and MCF-7 cells | mechanism | BC/OC research |
| hsa-miR-638 | miR-638 represses the stem cell characteristics of breast cancer cells by targeting E2F2 | 31410735 | MiR-638 represses the characteristics and behaviors of BCSCs by targeting E2F2. MiR-638 may be a potential target for breast cancer therapy | mechanism | BC/OC research |
| hsa-miR-638 | Exosomes released from pancreatic cancer cells are heterogeneous particle populations | Link | Exosomes form heterogeneous particle populations and nSMase2 may be involved in the exosomal uptake of miR-638 | mechanism | BC/OC research |
| hsa-miR-638 | miR-638 is a new biomarker for outcome prediction of non-small cell lung cancer patients receiving chemotherapy | 25952770 | That serum miR-638 levels are associated with the survival of NSCLC patients and may be considered a potential independent predictor for NSCLC prognosis | biomarker | BC/OC research |
| hsa-miR-638 | MiR-146a and miR-638 in BRCA1-deficient triple negative breast cancer tumors, as potential biomarkers for improved overall survival | 26835710 | MiR-146a and miR-638 are potential biomarkers for improved overall survival in patients with BRCA1-deficient TNBC tumors | biomarker | BC/OC research |
| hsa-miR-638 | MiRNA-638 promotes autophagy and malignant phenotypes of cancer cells via directly suppressing DACT3 | 28108314 | Our data in clinical tissue samples highlight miR-638 and?DACT3?as histological marker for cancer detection and their potentially therapeutic implications | biomarker | BC/OC research |
| hsa-miR-638 | MiR-638 inhibits cervical cancer metastasis through Wnt/β-catenin signaling pathway and correlates with prognosis of cervical cancer patients | 29271990 | MiR-638 might serve as a tumor suppressor. In the future, miR-638 might be regarded as a therapeutic target and a potential prognostic factor in human CC | biomarker | BC/OC research |
| hsa-miR-638 | MiR-638 inhibits cervical cancer metastasis through Wnt/β-catenin signaling pathway and correlates with prognosis of cervical cancer patients | 29271990 | In vitro assay showed that miR-638 overexpression suppressed cell migration and invasion of HeLa cells. The results of Western blot indicated that over-expression of miR-638 inhibited the activation of Wnt/β-catenin signaling pathway. | mechanism | BC/OC research |
| hsa-miR-638 | MiR-638 acts as a tumor suppressor gene in gastric cancer | 29296232 | In the cell lines, aberrant expression of miR-638 was related to the cell proliferation, cell cycle and invasion. We also found that SOX2 had a negative correlation with miR-638 in GC tissues, and miR-638 overexpression could decrease SOX2 expression level by directly binding the 3’-UTR of SOX2.?in vitro, down-regulating SOX2 by siRNA could counteract the effect of miR-638 inhibitor on GC cells proliferation and invasion | mechanism | BC/OC research |
Survival analysis
Pathways
| Enriched Terms | Cross Refer. |
|---|---|
| Adherens junction | KEGG |
| ECM-receptor interaction | KEGG |
| Pantothenate and CoA biosynthesis | KEGG |
| Oocyte meiosis | KEGG |
| Hippo signaling pathway | KEGG |