Dicer
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| Dicer | Prognostic value of Dicer expression in human breast cancers and association with the mesenchymal phenotype. | 19672267 | Assessment of Dicer expression may facilitate prediction of distant metastases for patients suffering from breast cancer. | biomarker | BC/OC research |
| Dicer | Dysregulated expression of dicer and drosha in breast cancer. | 21898071 | The decreased expression of Dicer and Drosha may play a role in down-regulation of miRNAs in breast cancer. | biomarker | BC/OC research |
| Dicer | Loss of Dicer expression is associated with breast cancer progression and recurrence. | 22821364 | Dicer protein plays a role in human BC progression and behaviour, and assessment of its expression could provide prognostic information in BC including the HER2-positive class.In invasive BC, loss of Dicer expression was associated with features of aggressive behaviour including higher histological grade, loss of hormone receptor and BRCA1 protein expression and with shorter disease-free survival (DFS). Moreover, loss of Dicer was predictive of better response to chemotherapy and to endocrine therapy. | biomarker | BC/OC research |
| Dicer | Prognostic Significance of Deregulated Dicer Expression in Breast Cancer | 24386264 | Dicer is an important prognostic marker in breast cancer and that its prognostic role may be subtype specific. | biomarker | BC/OC research |
| Dicer | Cancer Exosomes Perform Cell-Independent MicroRNA Biogenesis and Promote Tumorigenesis | 25446899 | Cancer exosomes induce tumor formation in a Dicer-dependent manner | mechanism | BCEXO research |
Survival analysis
Pathway
| Pathway Term | Reference DB | |
|---|---|---|
| Dicer | R-HSA-203927 | Reactome |
| Dicer | R-HSA-426486 | Reactome |
| Dicer | hsa05206:MicroRNAs in cancer | KEGG |