NANOG
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| NANOG | RNA interference-mediated silencing of NANOG reduces cell proliferation and induces G0/G1 cell cycle arrest in breast cancer cells | 22381696 | NANOG protein can bind to the promoter region of cyclinD1 and regulate cells cycle | mechanism | BC/OC research |
| NANOG | Prognostic significance of NANOG and KLF4 for breast cancer | 22528804 | Strong expression of NANOG is an indicator of a poor prognosis for breast cancer patients, whereas KLF4 is a favorable prognostic indicator | biomarker | BC/OC research |
| NANOG | Prognostic significance of NANOG and KLF4 for breast cancer | 22528804 | NANOG stimulates the growth and metastasis of breast cancer cells, whereas KLF4 inhibits these processes. | mechanism | BC/OC research |
| NANOG | The pluripotency factor nanog promotes breast cancer tumorigenesis and metastasis | 23770853 | The involvement of Nanog in breast cancer metastasis, and provide the basis for the reported correlation between Nanog expression and poor prognosis of human breast cancer patients | biomarker | BC/OC research |
| NANOG | The pluripotency factor nanog promotes breast cancer tumorigenesis and metastasis | 23770853 | Nanog promotes the migration and invasion of breast cancer cells | mechanism | BC/OC research |
| NANOG | PD‐L1 promotes OCT4 and Nanog expression in breast cancer stem cells by sustaining PI3K/AKT pathway activation | 28614911 | PD‐L1 positive effect on OCT‐4A and Nanog was dependent on AKT activation | mechanism | BC/OC research |
| NANOG | Immunohistochemical Expression of Nanog and Its Relation with Clinicopathologic Characteristics in Breast Ductal Carcinoma | 30220190 | Nanog is a biomarker for prognostic prediction in patients with breast cancer. However, further studies of Nanog are suggested to provide novel therapeutic targets for curing breast cance | biomarker | BC/OC research |
| NANOG | Exosomes enriched in stemness/metastatic-related mRNAS promote oncogenic potential in breast cancer | 26528758 | Stemness markers and enhance proliferation,migration and invasion abilities of neighboring cells | mechanism | BCEXO research |
Survival analysis
Pathway
| Pathway Term | Reference DB | |
|---|---|---|
| NANOG | Preimplantation Embryo (Homo sapiens) | Wikipathway |
| NANOG | Wnt Signaling Pathway and Pluripotency (Homo sapiens) | Wikipathway |
| NANOG | Interleukin-4 and 13 signaling (Homo sapiens) | Wikipathway |
| NANOG | Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways (Homo sapiens) | Wikipathway |
| NANOG | R-HSA-2892245 | Reactome |
| NANOG | R-HSA-2892247 | Reactome |
| NANOG | R-HSA-452723 | Reactome |
| NANOG | hsa04550:Signaling pathways regulating pluripotency of stem cells | KEGG |
| NANOG | hsa05205:Proteoglycans in cancer | KEGG |
| NANOG | Cardiac Progenitor Differentiation (Homo sapiens) | Wikipathway |