TLR5
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| TLR5 | Activation of Toll-Like Receptor 5 on Breast Cancer Cells by Flagellin Suppresses Cell Proliferation and Tumor Growth | 21427357 | TLR5 activation by flagellin mediates innate immune response to elicit potent antitumor activity in breast cancer cells themselves, which may serve as a novel therapeutic target for human breast cancer therapy | mechanism | BC/OC research |
| TLR5 | MAP1S Controls Breast Cancer Cell TLR5 Signaling Pathway and Promotes TLR5 Signaling-based Tumor Suppression | 24466264 | Elevated expression of MAP1S in response to flagellin feed-back regulated tumor inflammatory microenvironment in the late stages of TLR5 signaling through degradation of MyD88 in autophagy process | mechanism | BC/OC research |
| TLR5 | TLR5 is a new reporter for triple-negative breast cancer indicated by radioimmunoimaging and fluorescent staining | 31576678 | 125 I-antiTLR5 mAb was an ideal agent for non-invasive imaging of TLR5+ tumours; TLR5 may be as a novel molecular target for TNBC non-invasive diagnosis | mechanism | BC/OC research |
| TLR5 | TLR5 is a potential target in vivo monitoring triple-negative breast cancer | Link | TLR5 expressed on triple-negative breast cancer could be a molecular target for monitoring tumor growth in vivo and Flavopiridol may carry out its anti-tumor effect through CDK9-TLR5-NF-κB pathway. | mechanism | BC/OC research |
Survival analysis
Pathway
| Pathway Term | Reference DB | |
|---|---|---|
| TLR5 | hsa05321:Inflammatory bowel disease (IBD) | KEGG |
| TLR5 | Toll-like Receptor Signaling Pathway (Homo sapiens) | Wikipathway |
| TLR5 | Viral Acute Myocarditis (Homo sapiens) | Wikipathway |
| TLR5 | Simplified Depiction of MYD88 Distinct Input-Output Pathway (Homo sapiens) | Wikipathway |
| TLR5 | Toll-like Receptor Signaling (Homo sapiens) | Wikipathway |
| TLR5 | MyD88 cascade initiated on plasma membrane (Homo sapiens) | Wikipathway |
| TLR5 | Toll-Like Receptors Cascades (Homo sapiens) | Wikipathway |
| TLR5 | Pathogenic Escherichia coli infection (Homo sapiens) | Wikipathway |
| TLR5 | Regulation of toll-like receptor signaling pathway (Homo sapiens) | Wikipathway |
| TLR5 | hsa05134:Legionellosis | KEGG |