EEF1A1
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| EEF1A1 | Isoforms of elongation factor eEF1A may be differently regulated at post-transcriptional level in breast cancer progression | Link | EEF1A1 and EEF1A2 mRNAs contain distinct motifs in the UTRs and are differently regulated in cancer suggesting the possibility of their control by different cellular signals | mechanism | BC/OC research |
| EEF1A1 | Characterization of RNA in exosomes secreted by human breast cancer cell lines using next-generation sequencing | 24255815 | EEF1A1 distinguish exosomes produced by low metastatic breast cancer cell line (MDA-MB-436) from that produced by highly metastatic breast cancer cell line (MDA-MB-231) | mechanism | BCEXO research |
| EEF1A1 | Dissecting the expression of?EEF1A1/2?genes in human prostate cancer cells: the potential of EEF1A2 as a hallmark for prostate transformation and progression | 22095224 | Eukaryotic elongation factor 1A2 switch-on, observed in cultured tumour prostate cells and in human prostate tumour samples, may represent a feature of prostate cancer; in contrast, a minor involvement is assigned to EEF1A1 | mechanism | BC/OC research |
| EEF1A1 | P21 activated kinase 4 binds translation elongation factor eEF1A1 to promote gastric cancer cell migration and invasion | 28393218 | PAK4 interacted with eEF1A1 to promote migration and invasion of gastric cancer cells, thereby providing new insights into the function of PAK4 and eEF1A1 in the progression of gastric cancer | mechanism | BC/OC research |
| EEF1A1 | Contradictory mRNA and protein misexpression of EEF1A1 in ductal breast carcinoma due to cell cycle regulation and cellular stress | 30224719 | EEF1A1 mRNA levels in breast carcinomas are low due to EEF1A1 allelic copy number loss, found in 27% of tumors, and cell cycle-specific expression, because mRNA levels are high in G1 and low in proliferating cells | mechanism | BC/OC research |
| EEF1A1 | Genome-wide target interactome profiling reveals a novel EEF1A1 epigenetic pathway for oncogenic lncRNA MALAT1 in breast cancer | 31105998 | Knockdown of MALAT1 reduced cell proliferation and invasion by arresting cells at the G0/G1 phase. Ectopic overexpression of EEF1A1 reversed the altered tumor phenotypes induced by MALAT1 shRNA treatment | mechanism | BC/OC research |
Survival analysis
Pathway
| Pathway Term | Reference DB | |
|---|---|---|
| EEF1A1 | Translation Factors (Homo sapiens) | Wikipathway |
| EEF1A1 | Protein methylation (Homo sapiens) | Wikipathway |
| EEF1A1 | Protein methylation (Homo sapiens) | Wikipathway |
| EEF1A1 | Neutrophil degranulation (Homo sapiens) | Wikipathway |
| EEF1A1 | Neutrophil degranulation (Homo sapiens) | Wikipathway |
| EEF1A1 | Cellular response to heat stress (Homo sapiens) | Wikipathway |
| EEF1A1 | Cellular response to heat stress (Homo sapiens) | Wikipathway |
| EEF1A1 | Eukaryotic Translation Elongation (Homo sapiens) | Wikipathway |
| EEF1A1 | Eukaryotic Translation Elongation (Homo sapiens) | Wikipathway |
| EEF1A1 | Translation Factors (Homo sapiens) | Wikipathway |