TSG101
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| TSG101 | The breast cancer gene product TSG101: a regulator of ubiquitination? | 9253709 | As the UBC active site residue is replaced in the TSG101 sequence in a similar manner to several other members of the UBC family, we propose a role for TSG101 in regulating the ubiquitination of short-lived gene products | mechanism | BC/OC research |
| TSG101 | Aberrant splicing of the TSG101 tumor suppressor gene in human breast and ovarian cancers | 9773405 | Truncated TSG101 transcripts that probably represent splice variants are present in some breast and ovarian cancers, but there is no evidence to suggest that loss of this putative tumor suppressor gene plays a role in the molecular pathogenesis of these cancers | mechanism | BC/OC research |
| TSG101 | Aberrant expression of TSG101 in Taiwan Chinese breast cancer | 10930114 | The aberrant expression of TSG101 in breast cancer is associated with altered cell growth | mechanism | BC/OC research |
| TSG101 | Down-regulation of TSG101 by small interfering RNA inhibits the proliferation of breast cancer cells through the MAPK/ERK signal pathway | 21117030 | TSG101 may play a biological role through modulation of the MAPK/ERK signaling pathway in breast cancer | mechanism | BC/OC research |
| TSG101 | A knockout of the Tsg101 gene leads to decreased expression of ErbB receptor tyrosine kinases and induction of autophagy prior to cell death. | 22479596 | Defining particular functions for Tsg101 in processes such as signal transduction and lysosomal/endosomal trafficking | mechanism | BC/OC research |
| TSG101 | Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC | 21293856 | Tumour-derived exosomes interfere with the tumour-specific function of immune cells and constitute an additional mechanism how tumours escape from immune surveillance | mechanism | BCEXO research |
Survival analysis
Pathway
| Pathway Term | Reference DB | |
|---|---|---|
| TSG101 | R-HSA-162588 | Reactome |
| TSG101 | R-HSA-174490 | Reactome |
| TSG101 | R-HSA-917729 | Reactome |
| TSG101 | hsa04144:Endocytosis | KEGG |
| TSG101 | HIV Life Cycle (Homo sapiens) | Wikipathway |
| TSG101 | Endosomal Sorting Complex Required For Transport (ESCRT) (Homo sapiens) | Wikipathway |
| TSG101 | Ebola Virus Pathway on Host (Homo sapiens) | Wikipathway |