CASC3
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| CASC3 | Genomic analysis of the HER2/TOP2A amplicon in breast cancer and breast cancer cell lines | 18332872 | The amplification of the?HER2/TOP2A?region has been correlated with the overexpression of several additional genes, such as?CASC3,?CDC6,?RARA, and?SMARCE1 | mechanism | BC/OC research |
| CASC3 | Identification of Novel Breast Cancer Subtype-Specific Biomarkers by Integrating Genomics Analysis of DNA Copy Number Aberrations and miRNA-mRNA Dual Expression Profiling | 25961039 | ?In the luminal-A loss related Bayesian network motif, BRCA1 showed the most links with other biomarkers, including two miRNAs (miR-143 and miR-145) and 4 genes (CASC3, ITGA2B, BID, and LMNB1) | mechanism | BC/OC research |
| CASC3 | Methylation-regulated miR-124-1 suppresses tumorigenesis in hepatocellular carcinoma by targeting CASC3 | 27029030 | MiR-124-1-mediated downregulation of CASC3 resulted in the inactivation of p38-MAPK, JNK and ERK | mechanism | BC/OC research |
Survival analysis
Pathway
| Pathway Term | Reference DB | |
|---|---|---|
| CASC3 | Signaling by ROBO receptors (Homo sapiens) | Wikipathway |
| CASC3 | Nonsense-Mediated Decay (NMD) (Homo sapiens) | Wikipathway |
| CASC3 | Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens) | Wikipathway |
| CASC3 | RNA Polymerase II Transcription (Homo sapiens) | Wikipathway |