hsa-miR-34a
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| hsa-miR-34a | Molecular characterization of exosome-like vesicles from breast cancer cells | 24468161 | MCF-Exo also contains mir-34a, which regulates several genes including p53 | mechanism | BCEXO research |
| hsa-miR-34a | MiR-34a expression has an effect for lower risk of metastasis and associates with expression patterns predicting clinical outcome in breast cancer | 22102859 | MiR-34a expression activation is a marker of aggressive breast tumour phenotype it exerts an independent effect for a lower risk of recurrence or death from breast cancer | biomarker | BC/OC research |
| hsa-miR-34a | MicroRNA-34a: a potential therapeutic target in human cancer | 25032850 | Early studies have shown that miR-34a acts as a tumor-suppressor gene by targeting many oncogenes related to proliferation, apoptosis and invasion | mechanism | BC/OC research |
| hsa-miR-34a | The diagnostic role of microRNA-34a in breast cancer: a systematic review and meta-analysis | 28423566 | MiR-34a is a promising non-invasive biomarker in diagnosing BC | biomarker | BC/OC research |
| hsa-miR-34a | miR-34a directly targets tRNAiMet?precursors and affects cellular proliferation, cell cycle, and apoptosis | 29941603 | MiR-34a directly targets tRNAiMet precursors via AGO2-mediated cleavage, and that tRNAiMet functions as an oncogene, potentially representing a target molecule for therapeutic intervention | mechanism | BC/OC research |
| hsa-miR-34a | MicroRNA-34 family in breast cancer: from research to therapeutic potential | 30405848 | MiR-34s will open new opportunities for the development of novel therapeutic strategies and define a new approach in identifying potential biomarkers for early diagnosis of breast cancer | mechanism | BC/OC research |
| hsa-miR-34a | Evaluation of miRNA-9 and miRNA-34a as potential biomarkers for diagnosis of breast cancer in Iranian women | 30468908 | MiR-9 and miR-34a have the capability for distinguishing tumor tissues from healthy tissues and the study of their expression levels in tissue may be used as a biomarker for the diagnosis of breast cancer patients from healthy women | biomarker | BC/OC research |
| hsa-miR-34a | MicroRNA 34a suppresses breast cancer cell proliferation and invasion by targeting Notch1 | 30542388 | MiR-34a inhibitor transfection resulted in the opposite effects. In conclusion, the presented data indicated that miR-34a suppressed breast cancer cell proliferation and invasion, and its effect may partly be exerted by targeting Notch1 | mechanism | BC/OC research |
| hsa-miR-34a | Overexpression of miR-34a and miR-16 Synergistically Promotes Apoptosis in Breast Cancer Cells | Link | MiR-16 or miR-34a induced apoptosis individually | mechanism | BC/OC research |
Survival analysis
Pathways
| Enriched Terms | Cross Refer. |
|---|---|
| Thyroid hormone signaling pathway | KEGG |
| Prostate cancer | KEGG |
| Endometrial cancer | KEGG |
| Central carbon metabolism in cancer | KEGG |
| p53 signaling pathway | KEGG |
| Transcriptional misregulation in cancer | KEGG |
| Pathways in cancer | KEGG |
| Non-small cell lung cancer | KEGG |
| Endocytosis | KEGG |
| DNA replication | KEGG |