hsa-miR-301a
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| hsa-miR-301a | MicroRNA-301 mediates proliferation and invasion in human breast cancer | 21393507 | MiR-301 as a crucial oncogene in human breast cancer that acts through multiple pathways and mechanisms to promote nodal or distant relapses | mechanism | BC/OC research |
| hsa-miR-301a | Upregulated microRNA-301a in breast cancer promotes tumor metastasis by targeting PTEN and activating Wnt/β-catenin signaling | 24315818 | MiR-301a might be a potential target in breast cancer therapy | biomarker | BC/OC research |
| hsa-miR-301a | Upregulated microRNA-301a in breast cancer promotes tumor metastasis by targeting PTEN and activating Wnt/β-catenin signaling | 24315818 | MiR-301a directly targeted and suppressed PTEN, one negative regulator of the Wnt/β-catenin signaling cascade | mechanism | BC/OC research |
| hsa-miR-301a | Elevated miR-301a expression indicates a poor prognosis for breast cancer patients | 29396508 | MiR-301a should be considered, and novel therapeutic options are needed to target this aggressive miR-301a-positive type of breast cancer to reduce recurrence and the mortality rate | biomarker | BC/OC research |
| hsa-miR-301a | MiR-301a-3p Suppresses Estrogen Signaling by Directly Inhibiting ESR1 in ERα Positive Breast Cancer | 29763890 | ESR1 as a direct target of miR-301a-3p and suggest that miR-301a-3p likely contributes to development of estrogen independence, which leads to a more invasive phenotype of breast cancer | mechanism | BC/OC research |
| hsa-miR-301a | hsa-miR-301a- and SOX10-dependent miRNA-TF-mRNA regulatory circuits in breast cancer | 30814872 | Regulatory motifs involving miRNAs and TFs may be useful for understanding breast cancer regulation and for predicting new biomarkers | biomarker | BC/OC research |
| hsa-miR-301a | hsa-miR-301a- and SOX10-dependent miRNA-TF-mRNA regulatory circuits in breast cancer | 30814872 | The following significant circuits were characterized and validated bioinformatically by using web-based tools: SOX10→hsa-miR-301a→HOXA3, SOX10→hsa-miR-301a→KIT, and SOX10→hsa-miR-301a→NFIB | mechanism | BC/OC research |
| hsa-miR-301a | Molecular characterization of exosome-like vesicles from breast cancer cells | 24468161 | MCF-Exo contains a higher amount of hsa-miR-301a,and overexpression has been considered a negative prognostic indicator in lymph node-negative (LNN) invasive ductal breast cancer | mechanism | BCEXO research |
Survival analysis
Pathways
| Enriched Terms | Cross Refer. |
|---|---|
| Lipoic acid metabolism | KEGG |
| Chronic myeloid leukemia | KEGG |
| FoxO signaling pathway | KEGG |
| Fatty acid metabolism | KEGG |
| Glycosphingolipid biosynthesis - lacto and neolacto series | KEGG |
| Huntington's disease | KEGG |
| Metabolic pathways | KEGG |
| Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate | KEGG |
| Glycosaminoglycan biosynthesis - keratan sulfate | KEGG |
| Other types of O-glycan biosynthesis | KEGG |