TPP2
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| TPP2 | Tripeptidyl-peptidase II controls DNA damage responses and in vivo gamma-irradiation resistance of tumors. | 17671184 | TPPII can be targeted for inhibition of tumor therapy resistance. | biomarker | BC/OC research |
| TPP2 | Tripeptidyl-peptidase II controls DNA damage responses and in vivo gamma-irradiation resistance of tumors. | 17671184 | TPPII contains a BRCA COOH-terminal-like motif, contained within sequences of several proteins involved in DNA damage signaling pathways, and this motif was important for nuclear translocation of TPPII and stabilization of p53.TPPII connects signaling by cytosolic/mitochondrial and nuclear PIKK-dependent pathways | mechanism | BC/OC research |
| TPP2 | Tripeptidyl peptidase II in human oral squamous cell carcinoma. | 22986808 | Overexpression of TPP2 occurs frequently during oral carcinogenesis and might be associated with OSCC progression via SAC activation. | biomarker | BC/OC research |
Survival analysis
Pathway
| Pathway Term | Reference DB | |
|---|---|---|
| TPP2 | R-HSA-983168 | Reactome |
| TPP2 | Class I MHC mediated antigen processing & presentation (Homo sapiens) | Wikipathway |