DTX3L
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| DTX3L | DTX3L and ARTD9 inhibit IRF1 expression and mediate in cooperation with ARTD8 survival and proliferation of metastatic prostate cancer cells. | 24886089 | Our data strongly indicate that a crosstalk between STAT1, DTX3L and ARTD-like mono-ADP-ribosyltransferases mediates proliferation and survival of metastatic Pca(mPCa) cells. | biomarker | BC/OC research |
| DTX3L | DTX3L and ARTD9 inhibit IRF1 expression and mediate in cooperation with ARTD8 survival and proliferation of metastatic prostate cancer cells. | 24886089 | DTX3L and ARTD9 act together as repressors of the tumor suppressor IRF1 in mPCa cells. Furthermore, the present study shows that DTX3L together with STAT1 and STAT3 is implicated in cell migration of mPCa cells. | mechanism | BC/OC research |
| DTX3L | DTX3L is upregulated in glioma and is associated with glioma progression. | 28627634 | DTX3L could be a potential prognostic biomarker for glioma. | biomarker | BC/OC research |
| DTX3L | DTX3L is upregulated in glioma and is associated with glioma progression. | 28627634 | Knockdown of DTX3L by siRNA transfection increased glioma cell apoptosis. Moreover, suppression of DTX3L expression was shown to significantly inhibit the migration and invasion of glioma cells. | mechanism | BC/OC research |
Survival analysis
Pathway
| Pathway Term | Reference DB | |
|---|---|---|
| DTX3L | R-HSA-983168 | Reactome |
| DTX3L | hsa04330:Notch signaling pathway | KEGG |
| DTX3L | Notch Signaling Pathway (Homo sapiens) | Wikipathway |
| DTX3L | Class I MHC mediated antigen processing & presentation (Homo sapiens) | Wikipathway |