hsa-miR-195-5p
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| hsa-miR-195-5p | Upregulation of miR-195 increases the sensitivity of breast cancer cells to Adriamycin treatment through inhibition of Raf-1 | 23760062 | Expression of miR-195 or knockdown of Raf-1 can similarly reduce tumor cell survival but increase apoptosis through downregulation of Raf-1 and Bcl-2 and P-glycoprotein expression | mechanism | BC/OC research |
| hsa-miR-195-5p | MicroRNA-195-5p is a potential diagnostic and therapeutic target for breast cancer | 24402230 | Overexpression of miR-195-5p inhibited cell proliferation, reduced cell colony formation, suppressed cell migration and caused an accumulation of cells in the G1 phase of the cell cycle | mechanism | BC/OC research |
| hsa-miR-195-5p | Upregulation of miR-195 enhances the radiosensitivity of breast cancer cells through the inhibition of BCL-2 | 26309570 | Exogenetic miR-195 expression could significantly enhance the radiosensitivity of human breast cancer cells; this finding may be attributed to BCL-2 downregulation to promote radiation-induced apoptosi | mechanism | BC/OC research |
| hsa-miR-195-5p | MicroRNA-195 inhibits proliferation, invasion and metastasis in breast cancer cells by targeting FASN, HMGCR, ACACA and CYP27B1 | 26632252 | Hsa-miR-195 targets the genes of de novo lipogenesis, inhibits cell proliferation, migration, and invasion which potentially opens new avenues for the treatment of breast cancer | mechanism | BC/OC research |
| hsa-miR-195-5p | Differential expression of exosomal miRNAs between breast cancer patients with and without recurrence | 29050253 | Of 384 miRNAs, three miRNAs (miR-338-3p, miR-340-5p, and miR-124-3p) were significantly upregulated and eight (miR-29b-3p, miR-20b-5p, miR-17-5p, miR-130a-3p, miR-18a-5p, miR-195-5p, miR-486-5p, and miR-93-5p) were significantly downregulated in the patients with recurrence | biomarker | BCEXO research |
Survival analysis
Pathways
| Enriched Terms | Cross Refer. |
|---|---|
| Chronic myeloid leukemia | KEGG |
| Prostate cancer | KEGG |
| Fatty acid elongation | KEGG |
| Shigellosis | KEGG |
| Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate | KEGG |
| Bacterial invasion of epithelial cells | KEGG |
| Small cell lung cancer | KEGG |
| Protein processing in endoplasmic reticulum | KEGG |
| Mucin type O-Glycan biosynthesis | KEGG |
| Progesterone-mediated oocyte maturation | KEGG |