hsa-miR-195
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| hsa-miR-195 | Upregulation of miR-195 increases the sensitivity of breast cancer cells to Adriamycin treatment through inhibition of Raf-1 | 23760062 | Expression of miR-195 or knockdown of Raf-1 can similarly reduce tumor cell survival but increase apoptosis through downregulation of Raf-1 and Bcl-2 and P-glycoprotein expression. | mechanism | BC/OC research |
| hsa-miR-195 | MicroRNA-195 inhibits proliferation, invasion and metastasis in breast cancer cells by targeting FASN, HMGCR, ACACA and CYP27B1 | 26632252 | Hsa-miR-195 targets the genes of de novo lipogenesis, inhibits cell proliferation, migration, and invasion which potentially opens new avenues for the treatment of breast cancer. | biomarker | BC/OC research |
| hsa-miR-195 | MicroRNA-195 inhibits proliferation, invasion and metastasis in breast cancer cells by targeting FASN, HMGCR, ACACA and CYP27B1 | 26632252 | Ectopic expression of hsa-miR-195 in MCF-7 and MDA-MB-231 cells not only altered cellular cholesterol and triglyceride levels significantly but also resulted in reduced proliferation, invasion and migration. Over expression of hsa-miR-195 decreased the Mesenchymal markers expression and enhanced Epithelial markers. | mechanism | BC/OC research |
| hsa-miR-195 | Expression of tumor suppressors miR-195 and let-7a as potential biomarkers of invasive breast cancer | 29995098 | The analysis of miR-195 and let-7a can be used as a non-invasive biomarker for breast cancer detection. | biomarker | BC/OC research |
| hsa-miR-195 | Blood Circulating Exosomes Contain Distinguishable Fractions of Free and Cell-Surface-Associated Vesicles | 30868953 | Preliminary data indicated that detection of cancer-specific miRNA (miR-103, miR-191, miR-195) in exosomes associated with the fraction of red blood cells allowed to discriminate HFs and BCPs more precisely compared to cell-free exosomes circulating in plasma | biomarker | BCEXO research |
| hsa-miR-195 | Potentially predictive microRNAs of gastric cancer with metastasis to lymph node. | 21987613 | MiR-212 and miR-195 could be independent biomarkers in predicting the gastric cancer with metastasis to lymph node(LN). | biomarker | BC/OC research |
| hsa-miR-195 | Upregulation of miR-195 increases the sensitivity of breast cancer cells to Adriamycin treatment through inhibition of Raf-1 | 23760062 | Induction of miR-195 expression promoted tumor cell apoptosis and inhibited breast cancer cell viability, but induced the sensitivity of breast cancer cells to Adriamycin treatment and was associated with inhibition of Raf-1 expression in breast cancer cells. | biomarker | BC/OC research |
Survival analysis
Pathways
| Enriched Terms | Cross Refer. |
|---|---|
| Chronic myeloid leukemia | KEGG |
| Prostate cancer | KEGG |
| Fatty acid elongation | KEGG |
| Shigellosis | KEGG |
| Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate | KEGG |
| Bacterial invasion of epithelial cells | KEGG |
| Small cell lung cancer | KEGG |
| Protein processing in endoplasmic reticulum | KEGG |
| Mucin type O-Glycan biosynthesis | KEGG |
| Progesterone-mediated oocyte maturation | KEGG |