TAC1
Submitted by Anonymous on Wed, 10/30/2019 - 22:16
Pubmed
| Gene symble | Title | PMID | Curated descirption | Category | Literature category |
|---|---|---|---|---|---|
| TAC1 | Transformation of breast cells by truncated neurokinin-1 receptor is secondary to activation by preprotachykinin-A peptides | 16291810 | The oncogenic property of?Tac1?in breast cells involves concomitant expression of NK1-Tr and vice versa, consequently leading to the production of cytokines with growth promoting functions | mechanism | BC/OC research |
| TAC1 | Stromal-derived factor-1α induces a non-canonical pathway to activate the endocrine-linked?Tac1?gene in non-tumorigenic breast cells | 18316470 | Tac1 is relevant to breast cancer metastasis, to bone marrow where stromal cells have a significant facilitating function | mechanism | BC/OC research |
| TAC1 | RE-1-silencing transcription factor shows tumor-suppressor functions and negatively regulates the oncogenic TAC1 in breast cancer cells | 19246391 | REST knockdown in low-metastatic T47D cells and nontumorigenic MCF12A cells resulted in increases in TAC1 induction, proliferation, and migration | mechanism | BC/OC research |
| TAC1 | Biomarkers for detection and prognosis of breast cancer identified by a functional hypermethylome screen | 22647880 | Methylation of CDO1, CKM, CRIP1, KL and TAC1 correlated with clinical prognostic variables and was a significant prognosticator for poor overall survival in BC patients. | biomarker | BC/OC research |
Survival analysis
Pathway
| Pathway Term | Reference DB | |
|---|---|---|
| TAC1 | R-HSA-380095 | Reactome |
| TAC1 | R-HSA-416476 | Reactome |
| TAC1 | GPCR downstream signaling (Homo sapiens) | Wikipathway |
| TAC1 | GPCR ligand binding (Homo sapiens) | Wikipathway |
| TAC1 | Gastrin-CREB signalling pathway via PKC and MAPK (Homo sapiens) | Wikipathway |
| TAC1 | TNFs bind their physiological receptors (Homo sapiens) | Wikipathway |
| TAC1 | Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways (Homo sapiens) | Wikipathway |